Getting used to using your keyboard exclusively and leaving your mouse behind will make you much more efficient at performing any task on any Windows system. I use the following keyboard shortcuts every day:
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Windows key + R = Run menu
This is usually followed by:
cmd = Command Prompt
iexplore + "web address" = Internet Explorer
compmgmt.msc = Computer Management
dhcpmgmt.msc = DHCP Management
dnsmgmt.msc = DNS Management
services.msc = Services
eventvwr = Event Viewer
dsa.msc = Active Directory Users and Computers
dssite.msc = Active Directory Sites and Services
Windows key + E = Explorer
ALT + Tab = Switch between windows
ALT, Space, X = Maximize window
CTRL + Shift + Esc = Task Manager
Windows key + Break = System properties
Windows key + F = Search
Windows key + D = Hide/Display all windows
CTRL + C = copy
CTRL + X = cut
CTRL + V = paste
Also don't forget about the "Right-click" key next to the right Windows key on your keyboard. Using the arrows and that key can get just about anything done once you've opened up any program.
Keyboard Shortcuts
[Alt] and [Esc] Switch between running applications
[Alt] and letter Select menu item by underlined letter
[Ctrl] and [Esc] Open Program Menu
[Ctrl] and [F4] Close active document or group windows (does not work with some applications)
[Alt] and [F4] Quit active application or close current window
[Alt] and [-] Open Control menu for active document
Ctrl] Lft., Rt. arrow Move cursor forward or back one word
Ctrl] Up, Down arrow Move cursor forward or back one paragraph
[F1] Open Help for active application
Windows+M Minimize all open windows
Shift+Windows+M Undo minimize all open windows
Windows+F1 Open Windows Help
Windows+Tab Cycle through the Taskbar buttons
Windows+Break Open the System Properties dialog box
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